Search results for "Nuclear family"
showing 10 items of 31 documents
Family Activity Patterns as related to the symmetry in the division of labour in the family, children’s socialization to work and the significance of…
1986
The paper is based on empirical material collected in connection with the research project ‘Way of life in the family parental awareness of parenthood, and children’s social development’. The sample consisted of 212 families with both parents and a six-year-old child. It was relatively homogeneous with regard to the educational background of the parents. Comparisons were made between groups of families which differed with regard to (1) symmetry in the division of labour, (2) socialization of children to work, and (3) the relative significance of work vs. family life to the parents. Symmetry in the division of labour was strongly reflected in the family time consumption patterns and their co…
ADHD and DAT1: Further evidence of paternal over-transmission of risk alleles and haplotype
2010
Contains fulltext : 87259.pdf (Publisher’s version ) (Closed access) We [Hawi et al. (2005); Am J Hum Genet 77:958-965] reported paternal over-transmission of risk alleles in some ADHD-associated genes. This was particularly clear in the case of the DAT1 3'-UTR VNTR. In the current investigation, we analyzed three new sample comprising of 1,248 ADHD nuclear families to examine the allelic over-transmission of DAT1 in ADHD. The IMAGE sample, the largest of the three-replication samples, provides strong support for a parent of origin effect for allele 6 and the 10 repeat allele (intron 8 and 3'-UTR VNTR, respectively) of DAT1. In addition, a similar pattern of over-transmission of paternal ri…
Immunophenotypical comparison of Gaucher's and pseudo-Gaucher cells.
1996
An immunohistochemical study on bone marrow biopsies and spleens of patients with Gaucher's disease and chronic myeloid leukemia was performed to investigate the immunophenotype of Gaucher's cells and pseudo-Gaucher cells. A panel of antibodies was used which were reactive on paraffin-embedded tissues and directed against different hematopoietic lineage cells. Gaucher's cells and pseudo-Gaucher cells expressed a very similar immunophenotype and displayed an intense reaction for the monocytic antibodies tested, thus confirming their common origin and that they belong to the same system. The expression of HLA-DR antigens was much stronger in Gaucher's than in pseudo-Gaucher cells. This last f…
Postmodernistyczne przemiany w rodzinie
2018
Artykuł jest próbą syntezy przemian rodziny dokonujących się w epoce postmodernizmu. Sta-rano się pokazać przemiany w zakresie definiowania rodziny, liczby zawieranych małżeństw i mo-deli funkcjonujących w tej instytucji, przemiany w prokreacji oraz alternatywne do rodziny związki. Wnioski tych analiz prowadzą do stwierdzenia, że postmodernizm wpływa na współczesną rodziną, wywołując w niej dosyć wyraźnie zaznaczające się zmiany, ale ciągle to rodzina nuklearna pozosta-je dominującą formą życia małżeńsko-rodzinnego
Dynamic Family System Trajectories From Pregnancy to Child's First Year
2014
According to family systems theory, families consist of hierarchically ordered parts, from basic dyadic relations to marital and parental subsystems (Minuchin, 1985). In the transition to parenthood, family relationships change as the family system adapts to the new situation. Thechanges,suchasimprovementsanddeclines in relationship quality, are different and unique, depending on how emotions and responsibili- ties are shared in the family. For instance, fam- ilies with well-functioning relationships during pregnancy tend also to fare well in the postpar- tum period, whereas families with problematic relationships often experience further decline in their relationship quality across the tra…
The family in Italy: Cultural changes and implications for treatment
2012
In Italy family is characterized by strong ties and is based on mutual aid of all its members. In the last 20 years, the structure of families has been significantly influenced by demographic, economic and professional changes, determining a transition from a patriarchal to a nuclear family model, with a higher number of single-parent families, single-person households, childless couples, same-sex couples. However, this transition has been slower than that occurring in other countries, probably as an ongoing impact of prevalent Catholic ideology. Major demographic changes in Italian families include, 1) a decrease in the number of marriages, delays in getting married and an high number of c…
A case of disseminated BCG infection in a daughter of Italian immigrants in Switzerland
2022
Bacillus Calmette-Guérin (BCG) is a vaccine against tuberculosis and contains a live, attenuated strain of Mycobacterium bovis as its essential constituent. Being a live, attenuated strain with potential pathogenicity, BCG can cause different complications, both near the inoculation site and through blood dissemination, especially in patients with immunodeficiency. IFN-γR1 deficiency is an autosomal recessively inherited immunodeficiency characterized by predisposition to infections with intracellular pathogens, in particular mycobacteria.
 We report a rare case of chronic osteomyelitis lasting 30 years due to BCG in a woman with IFN-γR1 deficiency who had previous clinical history of …
A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q
2001
Bipolar affective disorder (BPAD), also known as manic depressive illness, is a severe psychiatric disorder characterized by episodes of mania and depression. It has a lifetime prevalence of approximately 1% in all human populations. In order to identify chromosomal regions containing genes that play a role in determining susceptibility to this psychiatric condition, we have conducted a complete genome screen with 382 markers (average marker spacing of 9.3 cM) in a sample of 75 BPAD families which were recruited through an explicit ascertainment scheme. Pedigrees were of German, Israeli and Italian origin, respectively. Parametric and non-parametric linkage analysis was performed. The highe…
Pigment variant of neuronal ceroid-lipofuscinosis
1995
A 6-year-old girl had progressive ataxia, and visual disturbances resulting in blindness. She died in her sleep at age 22 years. She shared with her sister and paternal relatives bilateral pes cavus deformities and impaired deep-tendon reflexes which suggested Charcot-Marie-Tooth disease. Her sister, who also had both polyneuropathy and a progressive central nervous system (CNS) disease, did not have pigmentary retinopathy. At autopsy, the patient was found to have neuronal ceroid-lipofuscinosis (NCL) marked by intraneuronal accumulation of autofluorescent granular lipopigments in ballooned perikarya and conspicuous extraneuronal pigmentation of subcortical grey matter, but without axonal s…
Filgrastim mobilization and collection of allogeneic blood progenitor cells from adult family donors: first interim report of a prospective German mu…
2002
Recombinant human granulocyte colony-stimulating factor (rhG-CSF) mobilized peripheral blood progenitor cells (PBPCs) from healthy individuals are a rapidly emerging alternative source to bone marrow for allogeneic transplantation. Although widely applied in the meantime, only limited information on feasibility and safety of mobilization and collection of PBPCs is currently available from prospective multicenter studies specifically designed to investigate this donation modality. This ongoing multicenter study on the performance as well as the short- and long-term safety profile of rhG-CSF-induced mobilization and collection of PBPCs was initiated in October 1999. The study is designed to r…